There are gaping holes in vaccine science, especially the critical role of microflora in mediating vaccine effects, including adverse ones.
Vaccine Injury: The Biological Plausibility of Microbial Predisposition – Part 2The purpose of these articles is to call attention to gaping holes in vaccine science, issues never before studied:1) How childhood vaccines may affect flora balance and colonization, and2) How existing flora (microbial predisposition) may affect vaccine response leading to injury.
The Critical Role of Microflora In Vaccine Injury
In Part 1, we explored microbes as the underlying beauty of diversity in explaining how children react differently to vaccines. It’s known gut dysbiosis contributes to inflammation and poor vaccine response. This means imbalanced flora leads to vaccine failure. Children born with imbalanced flora may be prone to powerful vaccine reaction of the immune system leading to injury. Important microbes such as protective Bifidobacteria may be reduced or absent.
Some groups with microbial predisposition based on ancestral dietary habits may be predisposed to vaccine reaction and higher risk of injury. How childhood vaccines affect flora balance, short and long-term, remains unknown. And there are no studies about how the infant microbiome may predispose a child to vaccine injury.
By the CDC’s own admission, African American boys may be one such group prone to vaccine injury: an increased risk of autism. One important microbial factor possibly explaining both poor vaccine response and vaccine injury is reduced or absent Bifidobacteria. Instead of doctors suggesting parents give their children Motrin or dangerous, glutathione-lowering Tylenol before and after vaccination, perhaps anti-inflammatory probiotics are in order to enhance vaccine response and protect from injury. This is the science of probiotics as vaccine adjuvants, except scientists aren’t considering how probiotics may guard from injury. They’re only interested in vaccine response to improve efficacy.
Before Dr. Brian Hooker’s paper detailing significantly increased risk of autism by MMR vaccination in African American boys was retracted by its publisher, even stripped of its title, the Mayo Clinic was busy pondering why the African American immune system produces twice as many antibodies to the current rubella vaccine as Caucasians and Hispanics. They have no explanation other than genetics in disregard of microbial regulation of genes and immune response.
Here’s Dr. Gregory Poland, head of the Mayo Clinic’s Vaccine Research Group and Editor-in-Chief of the journal Vaccine, wondering aloud (video):
“The vaccine in essence is working differently. The question is, why? It’s the same vaccine in human beings administered the same way and yet it stimulates a very different set of gene expression and protein secretion, that protein being antibody that protects us when we see the virus. We may be able to reduce the amount of side effects.”
What Dr. Poland is not factoring is gene-microbe interaction and how people have different flora balance. Why is the Mayo Clinic focused on genes when microbiota are known to switch genes on and off, regulating gene expression? Reducing risk of side effects may be better approached through microbial DNA testing to determine an individual’s flora balance prior to vaccination.
Dr. Hooker attempts to explain the discrepancy by way of vitamin D levels, known lower in African Americans while vitamin D deficiency is pandemic not based on skin color, but flora balance. Vitamin D isn’t just about sunshine as commonly touted by experts. Some studies paradoxically find vitamin D levels lowest in the brightest months. The rickets epidemic in the UK is considered a matter of low sun exposure and poor diet while beaches are polluted with sewage ten times over legal limits. Children in Bangladesh are not suffering rickets due to wearing too much sunblock. The epidemic is more likely tied to high rates of gestational diabetes leading to gut dysbiosis in newborns beginning in the womb. It’s no accident all the major gut diseases include vitamin D deficiency where these diseases are matters of microbial overgrowth. Microbes make and break vitamin D. They produce precursors of the hormone, vitamin D, and the enzymes responsible for its degradation. Moreover, small intestinal malabsorption due to gut dysbiosis leads to vitamin and mineral deficiency associated with hormonal imbalance. We’re only beginning to learn how gut microbiota affect hormone levels. Bifidobacteria control inflammation by way of increasinghormone-secreting endocrine cells and improving gut barrier function.
Dr. Hooker also cites a 2010 paper where the Hepatitis B vaccine administered at birth results in higher rates of autism in nonwhite boys. “Non-Hispanic white boys were 64% less likely to have autism diagnosis relative to nonwhite boys.” Armed with this information, why would any doctor allow an African American male newborn HepB vaccination within 12 hours of birth per cruel CDC schedule?
And what of newborns of all races and both genders potentially predisposed to vaccine injury based on microbial predisposition? Not only are genes passed from mother to child, but so are her microbes which interact with genes. With gut imbalances and diseases such as obesity, diabetes,Celiac and Crohn’s on the rise affecting future generations, we’re also seeing higher rates of vaccine injury.