Inaugural Gut Webinar With Christopher Kelley and Amelia

Thank you all for your interest and attendance on the inaugural Gut Webinar with Christopher Kelly, Amelia and myself! The turnout was amazing. We had great discussions on the various methods of testing gut function and some of the controversy.  3 participants had uBiome and others brought in integrative medicine tests that I really like such as CDSA/P (comprehensive digestive stool analysis with parasitology) from Genova, Doctor’s Data or Great Plains.

We will later post the transcript and some Q-A. If you missed it, a second is being planned! Will provide more details soon.

For those more interested in the diagnostic gut testing, they are available via Christopher or the newly launched iApothecary. If you are my client, Genova has set up a fantastic copay system ($109, Stool 2200; $149 Optimal urine organic acids, ONE) which is better than the cash pricing listed under Diagnostics.

Diagnostic Laboratories: Test Your Stools, Urine, Blood, Saliva for Knowledge and Tracking

 

Hardcore and Softcore Leaky Gut Kits

Here are a few kits that can help fast track gut health and optimal microbiome strengthening and conditioning. Bionic fiber is fantastic — it makes people lean, mean, clean and hawwwt. However, many with moderate to severe dysbiosis and intolerances to FODMAPS and fiber cannot tolerate the best prebiotics, oligosaccharides or inulin or cooked starches (RS Type 3 and 5). Consider diagnostic testing to find your targets and one of these kits to get your gut health back on track.

 

LEAKY GUT ‘KIT’ FOR RAPID RESULTS (SOFTCORE)

Leaky Gut ‘Kit’ (Softcore: mild to moderate dysbiosis)

Reviving, Restoring the Gut Lining and Ancestral Microbiome

Target Optimal Gut Health with the best tools available. Restore the garden in your gut that poor diets, gluten/dairy, antibiotics, synthetic birth control and stress demolished!

 

LEAKY GUT ‘KIT’ FOR RAPID RESULTS (HARDCORE)

Leaky Gut ‘Kit’ (Hardcore: moderate to severe dysbiosis)

Reviving, Restoring the Gut Lining and Ancestral Microbiome

Target Optimal Gut Health with the best tools available. Restore the garden in your gut that poor diets, gluten/dairy, antibiotics, synthetic birth control and stress demolished!

Bionic Fiber Got an Upgrade

Many products streamline how we can super power feed our 100 trillion friends and gut flora! Besides eating a great, diverse semi-Paleo/WAPF diet, consider adding in extra prebiotics to hit the magic threshold of ~ 40 to 50 grams daily of total daily fiber. Our ancestors certainly were able to obtain double or TRIPLE this amount. So if you are challenged and cannot chew buckets of roasted weeds and rough roots, consider a few scoops of high quality, pharmaceutical grade prebiotics.

Bionic Fiber = Super Fuel for Your Powerful 100 Trillion Friends in Your Gut Microbiota

Dr. Grace’s Bionic Fiber for Your Gut:  Step #4
Make a unique and personal blend of your favorite prebiotics. Prebiotics are fiber. The below list are superfoods for your beneficial gut flora which crowd out pathogens and opportunistic overgrowths of yeasts, parasites and bacteria. Mix 1 teaspoon or more of a diverse abundance of different types of fiber. These are the super fuels that stimulate growth of the guardians in the gut which protect your gut lining and, ultimately, your health and longevity. Your ancestral microbiome — Bifidobacteria longum, Akkermansia, Roseburia and Faecalibacterium — which protect your health, longevity and leanness love these super fuels below!
  • Hunter

    Hi Dr. Grace,

    Are you accepting new clients? I’ve sent a few messages on the Contact page, but haven’t heard anything back. Not sure if they’re going through.

    Thanks!

    • DrGracePharmD-Gut_Goddess

      Hunter

      Looking forward to chatting soon.

    • Kelly Jean

      Hi Hunter – Did Grace help you?

  • SavGeo

    I love that you’re now offering Genova testing!! So convenient and more affordable for those who can’t pay the often enormous fees of functional medicine practitioners who don’t accept insurance.

    • DrGracePharmD-Gut_Goddess

      SavGeo~

      Glad you like it!

  • Juan Marte

    Hi Dr Grace,

    I want to know whats the difference between taking GI sustain, Prephage or taking other prebiotics like inulin, acacia gum, psyllium husk?

    • DrGracePharmD-Gut_Goddess

      Juan

      GI Sustain contains healing mucilage which are like bandages for a wound.
      Prephage targets biofilms and killing of pathogenic E coli which reside and hide in Candida and other biofilm ‘fortresses’.
      Prebiotics are just food and fuel for the symbionts (good flora) and give structure to the GI tract (insoluble fiber mostly) as they are passing through.

      Testing is good to do because some fiber and FODMAPS also feed pathogens in the small intestines which worsen FODMAP intolerances. For instance Citrobacter will ferment FOS in inulin (but acacia and arabinogalactan do not; acacia and AG also selectively feed protective Akkermansia, Bifidobacteria longum which will lower opportunistic pathogens, yeasts/Candid and starch-fermenting Bifidobacterium animalis/adolescenis)

  • Juan Marte

    live in in the Dominican Rep( outside the US ) and its kind of hard sending stuff, i checked some companies you mention about testing. Which tests you recommend for gut issues?

  • Liz

    Hi Dr Grace, I cant seem to take l-glutamine. I think its raising my elevated ammonia?! Can you heal the gut with the mucilagenous herbs alone. Taking slippery elm, zinc atm. Thanks

    • DrGracePharmD-Gut_Goddess

      HI Liz

      Thank you for your questions. I believe some people’s guts do not transform glutamine or adequately use glutamine. I’m not sure why and it may be related to both local gut inflammation (mucositis/colitis) or gene variants (celiac HLA DQ2/8/2.5).

      Sometimes NAG works (if not allergic to crustaceans/shellfish since this is the source). N acetyl glucosamine.

      Honestly the state of the SAD gut is pretty sad. Even gut healing in Paleo diet folks is incomplete IMO and requires some proactive approaches such as
      –7 Steps and diversification of starches
      –really super high dosage probiotics
      –soil based microorganisms
      –getting outdoors/hiking/gardening/farming etc

      This covers the bases!

      Please let me know what works for you best. I’d love to hear what symptoms and signs resolve and if you have testing from pre- and post-interventions

      • Liz

        Thanks will try out the NAG

      • Liz

        Is there a dose of NAG youd recommend?

        • DrGracePharmD-Gut_Goddess

          I like NAG. It is very ancestral if you consider that humans cooked seafood, ate insects (raw/cooked) and still do (termites eaten in rural Africa as protein/probiotic sources!)

          One study in children used 3-6 grams NAG for pediatric IBD with improved intestinal permeability, gut inflammation and even remission and reversal of disease progression. No controls however, sadly.

          Second study showed improvements and reduced immunity and inflammatory markers in an animal model of MS, an autoimmune disorder involving myelin and brain degenerative lesions (secondary to intestinal permeability).

          I use Perm A Vite a lot — it has only a tiny amount of NAG but contains Epidermal Growth Factor.

          http://thegutinstitute.myshopify.com/products/perm-a-vite-powder-300-gms

          http://www.ncbi.nlm.nih.gov/pubmed/11121904

          Aliment Pharmacol Ther. 2000 Dec;14(12):1567-79.

          A pilot study of N-acetyl glucosamine, a nutritional substrate for glycosaminoglycan synthesis, in paediatric chronic inflammatory bowel disease.

          GlcNAc shows promise as an inexpensive and nontoxic treatment in chronic inflammatory bowel disease, with a mode of action which is distinct from conventional treatments. It may have the potential to be helpful in stricturing disease.

          Eight of the children given oral GlcNAc showed clear improvement, while four required resection. Of the children with symptomatic Crohn’s stricture, only 3 of 7 have required surgery over a mean follow-up of > 2.5 years, and endoscopic or radiological improvement was detected in the others. Rectal administration induced remission in two cases, clear improvement in three and no effect in two. In all cases biopsied there was evidence of histological improvement, and a significant increase in epithelial and lamina propria glycosaminoglycans and intracellular GlcNAc.

          Biol Chem. 2011 Nov 18;286(46):40133-41.

          N-acetylglucosamine inhibits T-helper 1 (Th1)/T-helper 17 (Th17) cell responses and treats experimental autoimmune encephalomyelitis.

          The sugar N-acetylglucosamine (GlcNAc) enhances N-glycan branching and inhibits T cell activity and adoptive transfer experimental autoimmune encephalomyelitis (EAE). Here, we report that oral GlcNAc inhibits T-helper 1 (Th1) and T-helper 17 (Th17) responses and attenuates the clinical severity of myelin oligodendrocyte glycoprotein (MOG)-induced EAE when administered after disease onset. Oral GlcNAc increased expression of branched N-glycans in T cells in vivo as shown by high pH anion exchange chromatography, MALDI-TOF mass spectroscopy and FACS analysis with the plant lectin l-phytohemagglutinin. Initiating oral GlcNAc treatment on the second day of clinical disease inhibited MOG-induced EAE as well as secretion of interferon-γ, tumor necrosis factor-α, interleukin-17, and interleukin-22. In the more severe 2D2 T cell receptor transgenic EAE model, oral GlcNAc initiated after disease onset also inhibits clinical disease, except for those with rapid lethal progression. These data suggest that oral GlcNAc may provide an inexpensive and nontoxic oral therapeutic agent for MS that directly targets an underlying molecular mechanism causal of disease.

          • Liz

            thanks Dr Grace. That’s most helpful ?

          • DrGracePharmD-Gut_Goddess

            You are welcome. The ‘permanent sealant’ for gut permeability is naturally the gut guardians. The iApothecary is undergoing upgrades so we will be open again shortly in ~ 2 days. Thanks for your patience.

  • Steve

    Is the iApothecary operational? I can put items in my cart, but can’t checkout… every credit card we try fails – I’ve used those cards on other sites, today even.

  • Bryan Agurcia

    Dr. Grace, I’ve tried to contact you via that via the gut institute website and have failed many times. I need help with some friends. Please let me know how you can help as my friends are desperate and slaves of big pharma! Thank you so much and your work is interstellar!!!