Gut Zoomer 3.0 Complete

A unique opportunity to take a close look at the microbial world that exists in our gut, and how it affects our daily functions.

VIEW A SAMPLE REPORT HERE

Description

The gut microbiome resides in your large intestine and is host to more than 1000 species of bacteria that perform certain important functions from shaping the immune system to influencing metabolism of nutrients to fortifying the intestinal mucosal barrier (gut barrier).

It is important to know the abundances of the bacteria that symbiotically live in the human gastrointestinal tractbecause imbalances in the gut microbiome may lead to gastrointestinal symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders.

The Gut Zoomer report provides you with actionable recommendations that include potential risks for:

Intestinal permeability (SCFA producing bacteria and tight junction integrity)
Intestinal disorders (IBS and IBD related bacteria)
Small Intestinal Bacterial Overgrowth (SIBO)- related bacteria
Cardiovascularhealth (inflammationinfluencing and TMAO-related bacteria)
Autoimmune health (celiac, Crohn’s, rheumatoid arthritis, etc)
Neurological health (MS, Parkinson’s, and more)
Liver diseases (cirrhosis, hepatitis, cholangitis, and more)
Metabolic health (Obesity, diabetes, etc)
Nutrition (Vitamin production, oxalate metabolism)
Microbiome and hormone connections (Beta-glucuronidase and Beta-glucosidase)
67 pathogenic bacteria
24 Intestinal parasites
8 viruses
5 Fungal or yeast species
5 worm species
6 antibiotic resistance genes measured

and newly added additional markers of functional digestive status:

Calprotectin
Pancreatic elastase 1
Bile acids
Cholic acid
Chenodeoxycholic acid
Deoxycholic acid
Lithocholic acid
Acetic acid
Butyric acid
Propionic acid
Valeric acid
Total SCFAs
ß-glucuronidase

The test performs the most comprehensive analysis available of your intestinal microbiomeecosystem from a simple one-time stool collection. This test examines the complex and intricate relative abundance of each species or genus measured, in relation to the rest of the ecosystem, to provide a unique perspective on the gut microbiome and its connection to disease and inflammation.

The functional digestive analytes aid healthcare providers in determining if deficiencies in digestive enzymes, bile, or other critical metabolites are root causes of gastrointestinal inflammatory symptoms.

The Vibrant Gut Zoomer^TM also provides patients with an actionable report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols.

Markers Measured

The Gut Zoomer^TM is the most comprehensive gut microbiome test available on the market to clinicians, including over 170 species and genus-level measurements, as well as phylum assessments and two diversity indexes. We also provide recommendations for 35 commonly used probiotic products that may be appropriate based on risks determined by lab test results. Vibrant’s proprietary microchip technology allows for simultaneous detection of DNA from almost 200 species and genera of microorganisms from a one-time collection of stool sample.

Bacteria include:

Commensals (including probiotics)
Acinetobacter
Actinomyces
Akkermansia
Akkermansia muciniphila
Alistipes
Alloprevotella
Anaerostipes
Atopobium
Atopobium parvulum
Bacillus coagulans
Bacillus subtilis
Bacteroidales
Bacteroides
Bacteroides caccae
Bacteroides vulgatus
Bacteroidetes
Bacteroidetes/Firmicutes ratio
Bifidobacterium
Barnesiella
Bifidobacteria
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium animalis subsp Lactis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium brevis
Bifidobacterium catenulatum
Bifidobacterium dentium
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium Longum
Bifidobacterium spp
Blautia
Blautia hydrogenotorophica
Bradyrhizobiaceae
Butyricicoccus
Butyricimonas
Butyrivibrio
Catenibacterium
Cedecea
Cetobacterium
Christensenellaceae minuta
Citrobacter
Clostridia clusters IV
Clostridia clusters XIVa
Clostridia clusters XVIII
Clostridiales Family XIV Incertae Sedis
Clostridium
Clostridium hathewayi
Clostridium ramosum
Clostridium symbiosum
Clotridiales Incertae Sedis IV,
Collinsella
Coprobacillus
Coprococcus
Dermabacter
Desulfovibrio piger
Desulfovibrio
Dialister invisus
Dorea
Dysgonomonas
Edwardsiella
Eggerthella lenta
Enterobacter
Enterobacter aerogenes
Enterobacteria
Enterobacteriaceae
Enterococcus
Enterococcus gallinarum
Escherichia
Escherichia coli
Escherichia coli Nissle
Eubacterium
Eubacterium rectale
Faecalibacterium prausnitzii
Faecalibacterium
Firmicutes
Fusobacteria
Fusobacterium
Haemophilus
Hafnia
Holdemania
Lachnospiraceae
Lactobacillaceae
Lactobacillus
Lactobacillus acidophillus
Lactobacillus animalis
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus fermentum
Lactobacillus murinus
Lactobacillus paracasei
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus ruminis
Lactobacillus sakei
Lactobacillus salivarius
Lactococcus
Leuconostoc
Marvinbryantia
Megamonas
Methanobrevibacter
Methanobrevibacter smithii
Micrococcus
Mitsuokella
Mycoplana
Odoribacter
Oscillospira
Paenibacillus
Parabacteroides
Paraprevotella
Pediococcus
Peptostreptococcus
Phascolarctobacterim
Porphyromonas
Porphyromonas gingivalis
Prevotella
Prevotella copri
Prevotellaceae /Bacteroidetes (P/B)
Propionibacterium
Propionibacterium freudenreichii
Proteobacteria
Proteus mirabilis
Pseudobutyrivibrio
Pseudoflavonifractor
Psuedomonas
Roseburia
Roseburia intestinalis
Ruminococcaceae
Ruminococcus
Ruminococcus bromii
Ruminococcus gnavus
Ruminococcus obeum
Saccharomyces boulardii
Solobacterium moorei
Staphylococcaceae
Staphylococcus
Staphylococcus epidermidis
Staphylococcus pasteuri
Streptococcus spp
Streptococcus thermophiles
Subdoligranulum
Tannerella
Turicibacter
Tyzzerella
Tyzzerella 4
Veillonella
Veillonellaceae
Weissella
Yokenella
Cedecea
Cetobacterium
Coprobacillus
Dysgonomonas
Enterobacter
Hafnia
Holdemania
Megamonas
Mitsuokella
Odoribacter
Paenibacillus
Parabacteroides
Paraprevotella
Porphyromonas
Pseudoflavonifractor
Subdoligranulum
Turicibacter
Weissella
Yokenella

Pathogenic bacteria include:

Clostridium difficile Toxin A
Clostridium difficile Toxin B
Campylobacter spp
Campylobacter jejuni
Campylobacter coli
Campylobacter upsaliensis
Plesiomonas shigelloides
Vibrio (parahaemolyticus)
Enteropathogenic E.coli (EPEC)
Enterotoxigenic E.coli (ETEC)Lt/St
E.coli O157
Shiga-Like Toxin Producing E.coli(STEC)Stx1/Stx2
Shigella/EIEC
Helicobacter pylori
Listeria
Vibrio (cholerae)
Enteroaggregative E.coli(EAEC)
Klebsiella pneumoniae
Edwardsiella tarda
Yersinia enterocolitica
Vibrio (vulnificus )
Salmonella
Cryptosporidium

Parasites include:

Cryptosporidium
Entamoeba histolytica
Giardia lamblia
Cyclospora cayetanensis
Chilomastix mesnili
Cyclospora spp.
Dientamoeba fragilis
Endolimax nana
Entamoeba coli
Pentatrichomonas hominis
Larval Nematode
Ascaris lumbricoides
Strongyloides stercoralis
Taenia solium
Schistosoma
Blastocystis hominis
Trichomonas hominis
Isospora belli
Fasciola/Fasciolopsis
Hymenolepis
Dipylidium caninum
Diphyllobothrium datum
Trichuris trichina
Enterobius vermcularis
Mansonella

Fungi include:

Candida albicans
Candida spp.
Geotrichum spp.
Microsporidium spp.
Rodotorula spp.
Ancylostoma duodenale
Necator americanus
Trichuris trichiura
Taenia spp.

Viruses include:

Adenovirus F40/41
Rotavirus A
Astrovirus
Norovirus GI
Norovirus GII
Sapovirus I
Sapovirus II
Sapovirus IV
Sapovirus V
Cytomegalovirus
Epstein Barr virus

and antibiotic resistance genes measured include:

Helicobacter – Clarithromycin
Helicobacter – Fluoroquinolones
Universal Microbiota Resistance Genes – b-lactamase
Universal Microbiota Resistance Genes – Fluoroquinolones
Universal Microbiota Resistance Genes – Macrolides
Universal Microbiota Resistance Genes – Vancomycin

With a highly accurate measurement of each microorganism’s relative abundance, the results will guide providers and their patients on interventions to address imbalance, enhance nutrient intake, and increase abundance of critical keystone microbes, while addressing problematic overgrowths of opportunistic or pathogenic microbes.

Symptoms

Imbalances in your gut microbiome may lead to the following symptoms or conditions:

Autoimmune conditions
Inflammatory Bowel Disease (Crohn’s and ulcerative colitis)
Irritable Bowel Syndrome
Celiac disease
Cardiovascular disease
Metabolic syndrome
Diabetes
Liver and gallbladder disease
Neurological disorders
Mood abnormalities
Skin rashes (eczema or dermatitis)
Inflammatory symptoms
Small intestinal bacterial overgrowth (SIBO)
Fatigue
Gas and bloating
Indigestion
Infections
Intestinal permeability (‘leaky gut syndrome’)
Nutrient deficiencies
GERD
Food sensitivities
Malnutrition

FAQ

Should I stop probiotic supplements before taking a Vibrant Gut ZoomerTM sample?

The Vibrant Gut Zoomer^TM measures microorganism 16sRNA from a person’s stool sample. The results reflect the relative abundance of these microorganisms (bacteria, candida yeast, parasites, and viruses) compared to a reference range at the time of the sample. Thus, if a person is using a probiotic supplement the days/weeks leading up to the sample collection, their sample will reflect the ecosystem as influenced by the probiotics.

Our practitioners usually like to use the Gut Zoomer^TM in one of two ways. They will either have the patient remove or discontinue the probiotic for ~2 weeks before sample collection. The sample will then represent a person’s “baseline” microbiome ecosystem and a practitioner can individually recommend probiotic supplementation from baseline. The second strategy would be to run a Gut Zoomer^TM about ~one month into probiotic supplement to determine if that particular product is affective for that individual.

Can you tell me about the Gut Zoomer^TM 16s RNA technology?

The Gut Zoomer^TM is a DNA test. PCR is used to amplify and extend products of genomic DNA in the stool sample and then Vibrant’s microarray technology is used to measure bacteria 16s RNA.

Does this report show all of the bacteria that are growing in my gut?

Over 1,000 microbial species have been identified in the human gastrointestinal tract, and research is still evolving in this area. Of all the bacterial species identified, only about 100 bacterial species have been associated with potential health outcomes based on existing scientific studies published in peer-reviewed journals. The Vibrant Gut Zoomer^TM measures those species identified as having the greatest impact on health and disease.

Are there other types of bacteria that may be causing symptoms that are not on this report?

The Gut Zoomer^TM looks at three different types of dysbiosis:

dysbiosis caused by a lack of good flora
an overgrowth of bacteria that could be considered opportunistic
a lack of diversity in the types of flora found on the sample.

In the process of putting together a clinical history that takes into account your symptoms, the Gut Zoomer^TM test provides multiple correlations/risk factors for certain disease states or metabolic abnormalities. Because this type of testing is still an emerging science, it could be that your symptoms are not explained by the bacteria found on the report, however, since the test provides disease and metabolic associations for ~105 bacteria, this is rare.

Does the check mark on the Gut Pathogen test indicate that the pathogen is present?

The check mark indicates that the pathogen has been detected in the sample at a level that is considered pathogenic. See Vibrant’s validation report that states limit of detection (LOD) for each pathogenic organism.

Does the Gut Zoomer^TM test for Candida?

Candida is included on the expanded Gut Zoomer Completepanel.

Does the Gut Zoomer^TM test for SIBO?

No. A stool test is never determinate for SIBO, as stool testing evaluates large bowel microorganism ecosystem and SIBO is a manifestation in the small bowel (SIBO = Small Intestinal Bacterial Overgrowth). However, there is a correlation with an overabundance of certain bacteria that are associated with SIBO. If SIBO is suspected, the provider should complete an extensive intake and review of symptoms and consider running Vibrant’s IBSSure^TM which includes anti-CdTB and anti-vinculin antibodies that have a strong positive correlation with positive SIBO diagnosis.

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